Endocrine changes after bariatric surgery: an integrative review
DOI:
https://doi.org/10.69849/wsf54z18Keywords:
bariatric surgery, postoperative period, endocrine changesAbstract
Bariatric surgery is an effective intervention for obesity and related metabolic disorders, significantly improving health and alleviating hormonal imbalances. However, it also induces complex endocrine changes that may lead to dysfunctions, affecting the somatotropic, gonadal, thyroid, pancreatic, and adrenal axes.
A review of peer-reviewed studies was conducted using the PRISMA guidelines, focusing on research involving obese patients whose endocrine parameters were evaluated during postoperative periods. The PubMed and Scopus databases were searched, with an initial identification of 44 articles; after applying the exclusion criteria, 22 studies were selected for the review.
According to the studies analyzed in an integrated manner, these hormonal changes reflect the systemic impact of bariatric surgery in reducing chronic inflammation, improving glycemic homeostasis, restoring impaired endocrine axes, and mitigating metabolic comorbidities. The synthesis of the findings reinforces that the benefits of the procedure go beyond weight loss, involving profound endocrine adaptations that contribute to the overall clinical improvement of patients.
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Copyright (c) 2026 Selma Maria Santos Moura, Julio Cesar Viana de Carvalho Junior, Mariana Isabela Beserra de Menezes, Vanessa da Silva Lima (Autor)
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